Lead Bioinformatician/Engineer

Lead Bioinformatician/Engineer (Pipelines and Infrastructure) @ Natera | Jobright.ai

Lead Bioinformatician/Engineer (Pipelines and Infrastructure) jobs in United States

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Natera · 3 weeks ago

Lead Bioinformatician/Engineer (Pipelines and Infrastructure)

United States

Full-time

Remote

Lead/Staff

$131K/yr - $164K/yr

4+ years exp

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. They are seeking a Lead Bioinformatics Engineer to own pipeline and infrastructure engineering for a research informatics team, focusing on enhancing workflows and supporting scientists in processing their own samples.

BiotechnologyLife ScienceHealthcareMedical DeviceFashionGeneticsHealth CareHealth DiagnosticsMedicalWomen's

H1B Sponsor Likely

Responsibilities

Maintain and improve our WDL workflows on AWS Batch and AWS HealthOmics

Own how new Nextflow workflows and existing WDL workflows run on one set of tooling and infrastructure

Make pipelines easier for scientists to run correctly without engineering support

Own the team's AWS infrastructure, managed as code in Terraform

Improve reliability, reproducibility, and observability across our compute environments

Build testing, monitoring, and alerting that surface failures before a scientist finds them

Build and harden internal tooling that reduces manual work for the team, including support for triage of production issues

Make new capabilities easier to test, document, and hand off

Use coding agents as a routine part of engineering here, for implementation, code review, investigation, and operational triage

You own what you ship regardless of what produced it, which means reviewing and testing agent-written code to the same standard as your own, and helping the team decide which of these tools are worth adopting

Partner with the team's science leads and data scientists on getting new methods into production pipelines and providing first line review of their changes, and with the production organization on handoff readiness for capabilities moving out of research

Qualification

PythonSoftware Engineering FundamentalsTestingDebuggingWDLNextflowSnakemakeCWLAWSTerraformLinuxContainerizationVersion ControlAI-assisted Workflow DevelopmentClear Written Communication

Required

Degree in Bioinformatics, Computer Science, Computational Biology, or a related field.

A degree is not a requirement

equivalent depth built through work counts fully

4+ years of software or pipeline engineering experience, preferably in a life sciences, sequencing, or production-adjacent setting. We count relevant experience from the point your work became substantially independent, however you got there

Demonstrated ownership of a system end to end. We mean operating it in production, not only building the first version

Strong Python and software engineering fundamentals, including testing and debugging practice

Experience with at least one workflow system

Snakemake, CWL, WDL, Nextflow, or similar

Real cloud experience, ideally AWS, including managing infrastructure as code. Terraform is what we use; another tool is fine

Solid Linux, container, and version control practice

You have built at least one AI-assisted workflow you still use, and you can say what it replaced and how you know it works

A track record of picking up unfamiliar tools quickly, more than any specific tool on your resume

Clear written communication, including documentation someone else can act on

Preferred

Direct WDL or Nextflow experience

Familiarity with AWS Batch or HealthOmics

Enough scientific curiosity to understand the biology behind the pipeline and ask useful questions about it

Benefits

Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents.

Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.

Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits

Generous employee referral program!

Company

Natera

Glassdoor

3.7

Cell-free DNA testing for oncology, women's and organ health.

Founded in 2004

San Carlos, California, USA

5001-10000 employees

https://www.natera.com/

H1B Sponsorship

Natera has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

80%

Represents job field similar to this job

Engineering and Development

Product Management

Management and Executive

Customer Service and Support

Sales

Legal and Compliance

Creatives and Design

Accounting and Finance

Human Resources

Trends of Total Sponsorships

*2026 (13)

2025 (90)

2024 (72)

2023 (37)

2022 (71)

2021 (64)

2020 (40)

Funding

Current Stage

Public Company

Total Funding

$1.16B

Key Investors

Matthew Rabinowitz,Roelof BothaSofinnova InvestmentsHarmony Partners,OrbiMed

2023-09-07Post Ipo Equity

• $250M

2022-11-15Post Ipo Equity

• $400.05M

2022-03-16Post Ipo Equity

• $5M

Leadership Team

Steve Chapman

CEO

Jonathan Sheena

Co-Founder, Board Member

Recent News

Morningstar.comNew Publication Establishes Strong Clinical Validation of Signatera™ for MRD Assessment in Lymphoma

2026-09-01

MarketScreenerNatera, Inc. Announces Clinical Validation Of Signatera For MRD Assessment In Lymphoma

2026-09-01

The Motley FoolBillionaire Stanley Druckenmiller Has Roughly 17% of His $5.2 Billion Duquesne Portfolio in Natera Stock. Is It Still a Buy After an 80% Run?

2026-08-29

Company data provided by crunchbase